Two-field NMR spectroscopy
Two-field NMR spectroscopy
The complexity of molecular systems accessible to NMR has increased dramatically with the advent of increasing magnetic fields (now up to 28 T for commercial systems). Yet, some properties of nuclear spins are more favorable at lower magnetic fields, typically in the range of ~1 T, the conventional fields of MRI and benchtop NMR. Here, we collaborate with the company Bruker Biospin to develop a new type of NMR spectrometer that couples two magnetic centers operating at two different magnetic fields: a high magnetic field (14 T) and a lower magnetic field (~1 T). The two magnetic centers are coupled by a sample shuttle, that can transfer the sample between the two centers in less than 100 ms. This systems allows us to manipulate nuclear spins at two different magnetic fields within a single NMR experiment.